[{"data":1,"prerenderedAt":48},["ShallowReactive",2],{"q-nurse-107-1-basic-medicine-054":3},{"subject":4,"subjectSlug":5,"subjectFullName":6,"question":7,"related":23},"基礎醫學","basic-medicine","基礎醫學(包括解剖學、生理學、病理學、藥理學、微生物學與免疫學)",{"id":8,"webId":9,"year":10,"session":11,"subject":4,"number":12,"stem":13,"options":14,"answer":19,"answerNote":20,"images":21,"explanation":22,"freq":11},"nurse-107-1-基礎醫學-054","nurse-107-1-basic-medicine-054",107,1,54,"在耳鼻喉科與家醫科門診，針對過敏性鼻炎與氣喘患者，處方以 Zileuton 治療，此藥物主要抑制下列何種酵素？",{"A":15,"B":16,"C":17,"D":18},"cyclooxygenase（COX）","angiotensin-converting enzyme（ACE）","lipoxygenase（LOX）","adenylate cyclase（AC）","C",null,[],"本題考點是 Zileuton 的酵素抑制標的。Zileuton 抑制 5-lipoxygenase(LOX),阻斷花生四烯酸轉化為白三烯(leukotrienes),減少支氣管收縮與發炎,用於氣喘與過敏性鼻炎,故選 C。A cyclooxygenase(COX)是 NSAID 與 aspirin 的標的,產生前列腺素而非白三烯;B angiotensin-converting enzyme(ACE)是降血壓 ACE 抑制劑的標的;D adenylate cyclase(AC)催化 cAMP 生成,與白三烯路徑無關,均非 Zileuton 作用點。",[24,28,32,36,40,44],{"webId":25,"stem":26,"number":11,"year":27,"session":11},"nurse-106-1-basic-medicine-001","下列有關表皮的敘述，何者正確？",106,{"webId":29,"stem":30,"number":31,"year":27,"session":11},"nurse-106-1-basic-medicine-002","下列何者在組織學特徵上可區分為絲球帶（zona glomerulosa）、束狀帶（zona fasciculata）、網狀帶（zona reticularis）？",2,{"webId":33,"stem":34,"number":35,"year":27,"session":11},"nurse-106-1-basic-medicine-003","顴弓（zygomatic arch）是由顴骨與下列何者共同組成？",3,{"webId":37,"stem":38,"number":39,"year":27,"session":11},"nurse-106-1-basic-medicine-004","下列何者參與形成踝關節？",4,{"webId":41,"stem":42,"number":43,"year":27,"session":11},"nurse-106-1-basic-medicine-005","下列何者是維持背部直立最重要的肌肉？",5,{"webId":45,"stem":46,"number":47,"year":27,"session":11},"nurse-106-1-basic-medicine-006","行走於前臂的內側，並與上臂深層的靜脈會合成腋靜脈的是那一條血管？",6,1783840739404]