[{"data":1,"prerenderedAt":48},["ShallowReactive",2],{"q-nurse-107-1-basic-medicine-071":3},{"subject":4,"subjectSlug":5,"subjectFullName":6,"question":7,"related":23},"基礎醫學","basic-medicine","基礎醫學(包括解剖學、生理學、病理學、藥理學、微生物學與免疫學)",{"id":8,"webId":9,"year":10,"session":11,"subject":4,"number":12,"stem":13,"options":14,"answer":19,"answerNote":20,"images":21,"explanation":22,"freq":11},"nurse-107-1-基礎醫學-071","nurse-107-1-basic-medicine-071",107,1,71,"抗 methicillin 金黃色葡萄球菌（MRSA）之抗藥性機制為何？",{"A":15,"B":16,"C":17,"D":18},"使用替代的代謝途徑","核糖體結構改變","產生 β-lactamase 分解 methicillin","細菌染色體突變造成青黴素結合蛋白（PBPs）構造改變代號：1106 頁次：8－8","D",null,[],"本題考點為 MRSA 對 methicillin 抗藥性的分子機制。依微生物學,β-lactam 抗生素靠結合細菌的青黴素結合蛋白（PBPs，即細胞壁交聯的轉肽酶）而抑制細胞壁合成;MRSA 帶 mecA 基因,製造低親和力的 PBP2a,使 methicillin 無法有效結合、細胞壁照常合成而抗藥,故選 D。A 錯,繞道另一代謝途徑是磺胺類抗藥概念。B 錯,核糖體結構改變是對胺基醣苷、四環黴素等蛋白質合成抑制劑的抗藥機制,與作用於細胞壁的 methicillin 無關。C 錯,methicillin 本就設計為耐 β-lactamase,故 MRSA 抗藥不靠此酶。",[24,28,32,36,40,44],{"webId":25,"stem":26,"number":11,"year":27,"session":11},"nurse-106-1-basic-medicine-001","下列有關表皮的敘述，何者正確？",106,{"webId":29,"stem":30,"number":31,"year":27,"session":11},"nurse-106-1-basic-medicine-002","下列何者在組織學特徵上可區分為絲球帶（zona glomerulosa）、束狀帶（zona fasciculata）、網狀帶（zona reticularis）？",2,{"webId":33,"stem":34,"number":35,"year":27,"session":11},"nurse-106-1-basic-medicine-003","顴弓（zygomatic arch）是由顴骨與下列何者共同組成？",3,{"webId":37,"stem":38,"number":39,"year":27,"session":11},"nurse-106-1-basic-medicine-004","下列何者參與形成踝關節？",4,{"webId":41,"stem":42,"number":43,"year":27,"session":11},"nurse-106-1-basic-medicine-005","下列何者是維持背部直立最重要的肌肉？",5,{"webId":45,"stem":46,"number":47,"year":27,"session":11},"nurse-106-1-basic-medicine-006","行走於前臂的內側，並與上臂深層的靜脈會合成腋靜脈的是那一條血管？",6,1783840739575]