[{"data":1,"prerenderedAt":48},["ShallowReactive",2],{"q-nurse-108-1-basic-medicine-055":3},{"subject":4,"subjectSlug":5,"subjectFullName":6,"question":7,"related":23},"基礎醫學","basic-medicine","基礎醫學(包括解剖學、生理學、病理學、藥理學、微生物學與免疫學)",{"id":8,"webId":9,"year":10,"session":11,"subject":4,"number":12,"stem":13,"options":14,"answer":19,"answerNote":20,"images":21,"explanation":22,"freq":11},"nurse-108-1-基礎醫學-055","nurse-108-1-basic-medicine-055",108,1,55,"生物製劑之蛋白質藥物 Etanercept 可治療風濕性關節炎（Rheumatoid arthritis），此藥物之藥理作用為何？",{"A":15,"B":16,"C":17,"D":18},"結合淋巴激素 IL-2","結合腫瘤壞死因子 TNF-α","結合干擾素 IFN-α","結合前列腺素 PGs","B",null,[],"本題考點是生物製劑 Etanercept 的分子標靶。依其結構，Etanercept 是可溶性 TNF-α 受體（p75）與 IgG Fc 的融合蛋白，會結合並中和循環中的腫瘤壞死因子 TNF-α，阻斷其促發炎訊號，用於類風濕性關節炎，故選 B。A 結合 IL-2 為 Basiliximab 類抗 IL-2 受體製劑的方向，非 Etanercept。C 結合干擾素 IFN-α 並非其標靶，臨床上反而有以 IFN 為藥物者。D 結合前列腺素 PGs 是 NSAIDs 抑制環氧化酶下游的概念，與生物製劑無關，皆不選。",[24,28,32,36,40,44],{"webId":25,"stem":26,"number":11,"year":27,"session":11},"nurse-106-1-basic-medicine-001","下列有關表皮的敘述，何者正確？",106,{"webId":29,"stem":30,"number":31,"year":27,"session":11},"nurse-106-1-basic-medicine-002","下列何者在組織學特徵上可區分為絲球帶（zona glomerulosa）、束狀帶（zona fasciculata）、網狀帶（zona reticularis）？",2,{"webId":33,"stem":34,"number":35,"year":27,"session":11},"nurse-106-1-basic-medicine-003","顴弓（zygomatic arch）是由顴骨與下列何者共同組成？",3,{"webId":37,"stem":38,"number":39,"year":27,"session":11},"nurse-106-1-basic-medicine-004","下列何者參與形成踝關節？",4,{"webId":41,"stem":42,"number":43,"year":27,"session":11},"nurse-106-1-basic-medicine-005","下列何者是維持背部直立最重要的肌肉？",5,{"webId":45,"stem":46,"number":47,"year":27,"session":11},"nurse-106-1-basic-medicine-006","行走於前臂的內側，並與上臂深層的靜脈會合成腋靜脈的是那一條血管？",6,1783840743366]