[{"data":1,"prerenderedAt":48},["ShallowReactive",2],{"q-nurse-111-1-basic-medicine-071":3},{"subject":4,"subjectSlug":5,"subjectFullName":6,"question":7,"related":23},"基礎醫學","basic-medicine","基礎醫學(包括解剖學、生理學、病理學、藥理學、微生物學與免疫學)",{"id":8,"webId":9,"year":10,"session":11,"subject":4,"number":12,"stem":13,"options":14,"answer":19,"answerNote":20,"images":21,"explanation":22,"freq":11},"nurse-111-1-基礎醫學-071","nurse-111-1-basic-medicine-071",111,1,71,"下列何者是影響自體免疫疾病易感性的主要遺傳因子？",{"A":15,"B":16,"C":17,"D":18},"CTLA-4（cytotoxic T lymphocyte-associated antigen 4）","FOXP3（forkhead box P3）","HLA（human leukocyte antigen）","AIRE（Autoimmune regulator）","C",null,[],"本題考點為影響自體免疫疾病易感性的主要遺傳因子。人類白血球抗原（HLA，即人類的 MHC 基因）多型性決定抗原呈遞的特性，是與最多自體免疫疾病相關聯的主要遺傳易感因子（如 HLA-B27 與僵直性脊椎炎、HLA-DR 與類風濕性關節炎等），故選 C。A 的 CTLA-4 與 T 細胞調節有關聯，但影響程度不如 HLA 廣泛。B 的 FOXP3 突變導致 IPEX 症候群，屬單基因調節 T 細胞缺陷。D 的 AIRE 突變造成 APECED（自體免疫多內分泌病變），也屬單基因。就『主要且廣泛』的遺傳易感因子而言，HLA 為正解。",[24,28,32,36,40,44],{"webId":25,"stem":26,"number":11,"year":27,"session":11},"nurse-106-1-basic-medicine-001","下列有關表皮的敘述，何者正確？",106,{"webId":29,"stem":30,"number":31,"year":27,"session":11},"nurse-106-1-basic-medicine-002","下列何者在組織學特徵上可區分為絲球帶（zona glomerulosa）、束狀帶（zona fasciculata）、網狀帶（zona reticularis）？",2,{"webId":33,"stem":34,"number":35,"year":27,"session":11},"nurse-106-1-basic-medicine-003","顴弓（zygomatic arch）是由顴骨與下列何者共同組成？",3,{"webId":37,"stem":38,"number":39,"year":27,"session":11},"nurse-106-1-basic-medicine-004","下列何者參與形成踝關節？",4,{"webId":41,"stem":42,"number":43,"year":27,"session":11},"nurse-106-1-basic-medicine-005","下列何者是維持背部直立最重要的肌肉？",5,{"webId":45,"stem":46,"number":47,"year":27,"session":11},"nurse-106-1-basic-medicine-006","行走於前臂的內側，並與上臂深層的靜脈會合成腋靜脈的是那一條血管？",6,1783840768673]