[{"data":1,"prerenderedAt":48},["ShallowReactive",2],{"q-nurse-113-1-basic-medicine-042":3},{"subject":4,"subjectSlug":5,"subjectFullName":6,"question":7,"related":23},"基礎醫學","basic-medicine","基礎醫學(包括解剖學、生理學、病理學、藥理學、微生物學與免疫學)",{"id":8,"webId":9,"year":10,"session":11,"subject":4,"number":12,"stem":13,"options":14,"answer":19,"answerNote":20,"images":21,"explanation":22,"freq":11},"nurse-113-1-基礎醫學-042","nurse-113-1-basic-medicine-042",113,1,42,"下列那個酵素主要負責B細胞的體細胞超突變（somatic hypermutation）？",{"A":15,"B":16,"C":17,"D":18},"RAG1（recombination-activating gene 1）","RAG2（recombination-activating gene 2）","TdT（terminal deoxynucleotidyl transferase）","AID（activation-induced cytidine deaminase）","D",null,[],"本題考點在於負責 B 細胞體細胞超突變的酵素。依免疫學，AID（活化誘導胞苷去胺酶）在生發中心使免疫球蛋白可變區基因產生點突變（體細胞超突變）並啟動類別轉換，以提升抗體親和力，故選 D。A RAG1、B RAG2 負責早期的 V(D)J 基因重組；C TdT 於重組時隨機加入核苷酸增加多樣性，皆屬淋巴球發育早期的機制，非成熟 B 細胞的超突變，故錯。",[24,28,32,36,40,44],{"webId":25,"stem":26,"number":11,"year":27,"session":11},"nurse-106-1-basic-medicine-001","下列有關表皮的敘述，何者正確？",106,{"webId":29,"stem":30,"number":31,"year":27,"session":11},"nurse-106-1-basic-medicine-002","下列何者在組織學特徵上可區分為絲球帶（zona glomerulosa）、束狀帶（zona fasciculata）、網狀帶（zona reticularis）？",2,{"webId":33,"stem":34,"number":35,"year":27,"session":11},"nurse-106-1-basic-medicine-003","顴弓（zygomatic arch）是由顴骨與下列何者共同組成？",3,{"webId":37,"stem":38,"number":39,"year":27,"session":11},"nurse-106-1-basic-medicine-004","下列何者參與形成踝關節？",4,{"webId":41,"stem":42,"number":43,"year":27,"session":11},"nurse-106-1-basic-medicine-005","下列何者是維持背部直立最重要的肌肉？",5,{"webId":45,"stem":46,"number":47,"year":27,"session":11},"nurse-106-1-basic-medicine-006","行走於前臂的內側，並與上臂深層的靜脈會合成腋靜脈的是那一條血管？",6,1783840770967]