[{"data":1,"prerenderedAt":48},["ShallowReactive",2],{"q-nurse-113-2-basic-medicine-024":3},{"subject":4,"subjectSlug":5,"subjectFullName":6,"question":7,"related":24},"基礎醫學","basic-medicine","基礎醫學(包括解剖學、生理學、病理學、藥理學、微生物學與免疫學)",{"id":8,"webId":9,"year":10,"session":11,"subject":4,"number":12,"stem":13,"options":14,"answer":19,"answerNote":20,"images":21,"explanation":22,"freq":23},"nurse-113-2-基礎醫學-024","nurse-113-2-basic-medicine-024",113,2,24,"Familial breast and ovarian carcinoma syndrome 的突變基因為何？",{"A":15,"B":16,"C":17,"D":18},"PTEN","NF1","PTCH","BRCA1 and BRCA2","D",null,[],"本題考點在於遺傳性乳癌卵巢癌症候群的致病基因。依腫瘤遺傳學，家族性乳癌與卵巢癌症候群（familial breast and ovarian carcinoma syndrome）由 BRCA1 與 BRCA2 抑癌基因的胚系突變造成，兩者參與 DNA 雙股斷裂的同源重組修復，失能後突變累積致癌，故選 D。A PTEN 對應 Cowden 症候群。B NF1 對應第一型神經纖維瘤病。C PTCH 對應 Gorlin（基底細胞痣）症候群，皆非本症候群的主要突變基因。",1,[25,29,32,36,40,44],{"webId":26,"stem":27,"number":23,"year":28,"session":23},"nurse-106-1-basic-medicine-001","下列有關表皮的敘述，何者正確？",106,{"webId":30,"stem":31,"number":11,"year":28,"session":23},"nurse-106-1-basic-medicine-002","下列何者在組織學特徵上可區分為絲球帶（zona glomerulosa）、束狀帶（zona fasciculata）、網狀帶（zona reticularis）？",{"webId":33,"stem":34,"number":35,"year":28,"session":23},"nurse-106-1-basic-medicine-003","顴弓（zygomatic arch）是由顴骨與下列何者共同組成？",3,{"webId":37,"stem":38,"number":39,"year":28,"session":23},"nurse-106-1-basic-medicine-004","下列何者參與形成踝關節？",4,{"webId":41,"stem":42,"number":43,"year":28,"session":23},"nurse-106-1-basic-medicine-005","下列何者是維持背部直立最重要的肌肉？",5,{"webId":45,"stem":46,"number":47,"year":28,"session":23},"nurse-106-1-basic-medicine-006","行走於前臂的內側，並與上臂深層的靜脈會合成腋靜脈的是那一條血管？",6,1783840771185]