[{"data":1,"prerenderedAt":48},["ShallowReactive",2],{"q-nurse-114-1-basic-medicine-039":3},{"subject":4,"subjectSlug":5,"subjectFullName":6,"question":7,"related":23},"基礎醫學","basic-medicine","基礎醫學(包括解剖學、生理學、病理學、藥理學、微生物學與免疫學)",{"id":8,"webId":9,"year":10,"session":11,"subject":4,"number":12,"stem":13,"options":14,"answer":19,"answerNote":20,"images":21,"explanation":22,"freq":11},"nurse-114-1-基礎醫學-039","nurse-114-1-basic-medicine-039",114,1,39,"下列有關doxorubicin的描述，何者錯誤？",{"A":15,"B":16,"C":17,"D":18},"可治療急性淋巴球性白血病","可治療肉瘤","具有劑量依賴性的心臟毒性","可抑制topoisomerase I 活性","D",null,[],"本題考點在於 doxorubicin 的藥理特性，本題為反向題，要找出錯誤敘述。依藥理，doxorubicin 屬蒽環類抗癌藥，其作用機轉是嵌入 DNA 並抑制「topoisomerase II」（非 topoisomerase I）並產生自由基，故 D 所述抑制 topoisomerase I 為錯誤，選 D。A 正確，可用於急性淋巴球性白血病；B 正確，對多種肉瘤有效；C 正確，其標誌性副作用為劑量依賴、累積性的心臟毒性。",[24,28,32,36,40,44],{"webId":25,"stem":26,"number":11,"year":27,"session":11},"nurse-106-1-basic-medicine-001","下列有關表皮的敘述，何者正確？",106,{"webId":29,"stem":30,"number":31,"year":27,"session":11},"nurse-106-1-basic-medicine-002","下列何者在組織學特徵上可區分為絲球帶（zona glomerulosa）、束狀帶（zona fasciculata）、網狀帶（zona reticularis）？",2,{"webId":33,"stem":34,"number":35,"year":27,"session":11},"nurse-106-1-basic-medicine-003","顴弓（zygomatic arch）是由顴骨與下列何者共同組成？",3,{"webId":37,"stem":38,"number":39,"year":27,"session":11},"nurse-106-1-basic-medicine-004","下列何者參與形成踝關節？",4,{"webId":41,"stem":42,"number":43,"year":27,"session":11},"nurse-106-1-basic-medicine-005","下列何者是維持背部直立最重要的肌肉？",5,{"webId":45,"stem":46,"number":47,"year":27,"session":11},"nurse-106-1-basic-medicine-006","行走於前臂的內側，並與上臂深層的靜脈會合成腋靜脈的是那一條血管？",6,1783840772110]