[{"data":1,"prerenderedAt":48},["ShallowReactive",2],{"q-nurse-114-3-basic-medicine-038":3},{"subject":4,"subjectSlug":5,"subjectFullName":6,"question":7,"related":24},"基礎醫學","basic-medicine","基礎醫學(包括解剖學、生理學、病理學、藥理學、微生物學與免疫學)",{"id":8,"webId":9,"year":10,"session":11,"subject":4,"number":12,"stem":13,"options":14,"answer":19,"answerNote":20,"images":21,"explanation":22,"freq":23},"nurse-114-3-基礎醫學-038","nurse-114-3-basic-medicine-038",114,3,38,"關於質子幫浦抑制劑（proton pump inhibitors, PPIs），下列敘述何者錯誤？",{"A":15,"B":16,"C":17,"D":18},"會明顯減少 clopidogrel 的抗血小板活性","不能使用在 aspirin 所造成的消化性潰瘍","應該在飯前 30～60 分鐘服用","可能會減少鈣的吸收，增加骨折的風險","B",null,[],"本題考點在於質子幫浦抑制劑(PPI)的臨床特性，為反向題，須挑出錯誤敘述。依適應症判斷，aspirin等NSAID造成的消化性潰瘍正是PPI的核心治療與預防用藥，故(B)敘述「不能使用在aspirin所造成的消化性潰瘍」為錯誤，選B。其餘皆正確：(A)PPI(尤其omeprazole)會抑制CYP2C19，減少clopidogrel活化而降低抗血小板效果；(C)PPI需在飯前30～60分鐘服用，以在餐後幫浦活化時達到血中濃度高峰；(D)長期使用會影響鈣吸收並增加骨折風險，皆屬正確描述。",1,[25,29,33,36,40,44],{"webId":26,"stem":27,"number":23,"year":28,"session":23},"nurse-106-1-basic-medicine-001","下列有關表皮的敘述，何者正確？",106,{"webId":30,"stem":31,"number":32,"year":28,"session":23},"nurse-106-1-basic-medicine-002","下列何者在組織學特徵上可區分為絲球帶（zona glomerulosa）、束狀帶（zona fasciculata）、網狀帶（zona reticularis）？",2,{"webId":34,"stem":35,"number":11,"year":28,"session":23},"nurse-106-1-basic-medicine-003","顴弓（zygomatic arch）是由顴骨與下列何者共同組成？",{"webId":37,"stem":38,"number":39,"year":28,"session":23},"nurse-106-1-basic-medicine-004","下列何者參與形成踝關節？",4,{"webId":41,"stem":42,"number":43,"year":28,"session":23},"nurse-106-1-basic-medicine-005","下列何者是維持背部直立最重要的肌肉？",5,{"webId":45,"stem":46,"number":47,"year":28,"session":23},"nurse-106-1-basic-medicine-006","行走於前臂的內側，並與上臂深層的靜脈會合成腋靜脈的是那一條血管？",6,1783840773034]